MRC Social, Genetic and Developmental Psychiatry Centre
De Crespigny Park
London SE5 8AF
Role in project
The IoP is the central location for manual-based development of standard procedures for recruitment, and psychometric and behavioural characterization of adolescent subjects (WP4). It is also the central site for neuroimaging standardization (WP5). It will carry out recruitment and characterization of adolescents, including psychometric and behavioural characterization, neuroimaging analysis and acquisition of blood for genetic analysis (WP6). The SGDP centre will be the site of storage of all blood samples. DNA extraction and genotyping will be carried out, and the IoP will be the central site for the identification of genetic variations and tagging SNPs using bioinformatics methods (WP8).
Professor Dr. Gunter Schumann
Profile: please click on this link
Phone: +44 (20) 7848 5314
Fax: +44 (20) 7848 0895
Hannah Jacobs: Team Administrator
Phone: +44(0)207 848 5395
Fax: +44(0)207 848 0940
Prof. Dr. Peter McGuffin: Director of SGDP Centre
Prof. Dr. Gareth Barker: Professor of Magnetic Resonance Physics
Prof. Dr. Steve Williams: Head of Neuroimaging Research Group
Dr. Gerome Breen: Research Fellow with Status of Lecturer
Dr. Patricia Conrod: Clinical Psychologist and Clinical Lecturer
Dr. Sylvane Desrivieres: Senior Research Worker
The history of the Institute of Psychiatry
The Institute of Psychiatry is a postgraduate institute of the University of London and, since August 1997, a school of King’s College London. Opened in 1923, it is the only postgraduate institution in the United Kingdom devoted to the study and practice of psychiatry and related disciplines. It shares the same site as the Maudsley Hospital which, until recently was part of the Maudsley and Bethlem NHS Trust, and is now part of the South London and Maudsley NHS Trust (one of the largest mental health Trusts in England).
The Institute of Psychiatry is the largest academic community in Europe devoted to the study and prevention of mental health problems. It is based next to the Maudsley Hospital and has close ties with the South London and Maudsley NHS Trust (SLAM). The Institute and SLAM work together to establish the best care for people who suffer from mental health problems, by pursuing excellence in research, development and teaching.
The Institute’s greatest strength is the interdisciplinary nature of both our research strategy and our educational activities providing unique opportunities for students. In the 2001 Research Assessment Exercise the highest possible rating was awarded to the Institute in recognition of the international quality of our research.
Specialised postgraduate programmes are taught in relatively small student groups. Close contact occurs between staff and students throughout the programmes which enables students to become part of the dialogue of their chosen discipline. Teaching by staff with research and clinical expertise allows students to gain specialist knowledge in topics related to psychiatry, psychology, and basic and clinical neuroscience and thus to develop their careers as clinicians, therapists, researchers and educators.
The Institute comprises the following academic departments:
• Biostatistics and Computing
• Child and Adolescent Psychiatry
• Forensic Mental Health Science
• Health Service and Population Research
• Clinical Neuroscience
• Psychological Medicine and Psychiatry
• Social, Genetic and Developmental Psychiatry Research
Major research activities of the Institute of Psychiatry
Scientists, therapists and doctors at the Institute of Psychiatry work to discover what causes mental health problems and diseases of the brain to help find new treatments – and ways of preventing them in the first place. Essentially, the Institute serves to find out what makes parts of the brain work differently, studying what events, circumstances and substances can affect mental health, trying out new ways of caring for people. The main areas of research include alcohol, nicotine and heroin addictions, depression, bipolar disorder, attention deficit hyperactivity disorder, autism spectrum disorders, eating disorders, schizophrenia, stress and post traumatic stress disorder.
Summary of experience relevant to IMAGEN
The IoP has experience in neuroimaging standardization, acquisition and processing, behavioural functional neuroimaging, and human cognitive and behavioural tasks. It also has experience in the recruitment of large cohorts, psychometric and behavioural characterization. The IoP also has extensive genetics experience, in DNA handling and extraction, DNA banking, differential expression techniques, SNP discovery and selection, and genotyping. Clinical experience includes substance use disorders, affective and anxiety disorders, ADHD, antisocial personality disorder/psychopathy and eating disorders.
Prof. Schumann holds a Chair in Addiction Biology and is Head of the Section of Addiction Biology at the KCL. He has extensive experience in coordinating multidisciplinary research teams in the context of the German National Genome Research Network and the German Addiction Research Network. His area of expertise covers gene-neuroimaging studies, translational studies and multicentric genetic studies on various drug use-related phenotypes. Dr. Sylvane Desrivieres has extensive experience in molecular and functional genetic research. Dr. Gerome Breen is a bioinformatics expert. Dr. Patricia Conrod has extensive experience in assessment instruments that cover addictive, impulsive and/or reward seeking behaviour. Prof. Dr. Steve Williams holds a Chair in of Imaging Sciences and is Head of the Neuroimaging Research Group at the KCL. He is interested in the development of novel neuroimaging techniques and has recently conducted a multicentric behavioural fMRI study. Dr. Laurence Reed is an experienced expert in psychiatric and behavioural functional neuroimaging.